Nanotechnology of surface active substances.

Investigation of Chiral Active Substances

Status Last revised 1993 Previous titles/other references Clinical Investigation of Chiral Active Substances/ III/3501/91 Additional Notes This note for guidance considers active substances with one or more stereogenic centres which display chirality but not constitutional isomerism or cis/trans isomerism. It should be read in conjunction with Directive 65/65/EEC as amended and Directive 75/318...

Medical Uses: Biologically Active Substances

Influence of Natural Sources of Biologically Active Substances on Livestock and Poultry Reproduction

Synthetic hormones and bioactive substances (vitamins, pigments and isoflavons) which have been used in the feed industry are accumulated in milk, meat and eggs. It is suspected that these are responsible for a number of side-effects such as carcinogenesis, liver and kidney damage, allergies in consumers. Furthermore the synthetic hormones, vitamins, pigments are less active than those extracte...

Discovery of active site of vinblastine as application of nanotechnology in medicine

Objective(s): Vinblastine is antimitotic, anticancer medicine that disturbs normal microtubule formation and favours depolymerisation. Structural study and finding the active site of vinblastine are the targets of this research.   Materials and Methods: Vinblastine was optimized in vacuum and then in different solvents by Density Functional Theory (DFT) method. Nuclear Magnetic Resonance (NMR) ...

Increasing the Efficacy of Electrolyte Active Substances

An adjuvant composition containing a) one or more alkyl glucamides of the formula (I), wherein R1 represents a linear or branched alkyl group having 5 to 9 carbon atoms, R2 represents an alkyl group having 1 to 3 carbon atoms; b) at least one water-soluble ammonium salt, preferably selected from the group consisting of ammonium sulfate, ammonium nitrate, ammonium nitrate urea, ammonium phosphat...